|
| Study | n/design | Mean BMI
kg/m2 | Intervention(s)
(mean values in cmH2O) | Measurements when | Gas exchange | Symptoms | Sleep |
|
| Mokhlesi et al. [36] | 75/Retro | 51 | CPAP = 14
Bilevel
PAP = 18/13* | Median = 84 d | PCO2 54 to 49 mmHg;
α to adherence hours
| | |
|
| Piper et al. [37] | 36/PR | 53 | CPAP = 14**
Bilevel
PAP = 16/10* | 3 months | PCO2 5.8 v. 6.9
mmHg | Sleepiness both groups; QOL > on bi-level PAP | Bilevel PAP better sleep quality |
|
| Hida et al. [38] | 26/PNR | 36 | CPAP | 3–6 months | | Sleepiness QOL | |
|
| Banerjee et al. [39] | 23/PNR | 59 | CPAP = 14 | “later date” | TST < 80 and 90% | | AHI,REM
|
|
| Berger et al. [23] | 23/Retro | 56 | CPAP = 13
Bilevel PAP 18/8 | Average of 14 months | PCO2 55 to 45
mmHg | | |
|
| Storre et al. [47] | 10/Prospective | 42 | Bilevel PAP 15/6
AVAPS 16/5 | 6 weeks | PCO2 47 to 42 in AVAPS and 46 in Bi-level PAP | Anxiety,social functioning | Arousals, REM, RDI, AHI |
|
| Pérez De Llano et al. [40] | 54/Retro | 44 | Initial bilevel
PAP settings 10/6 | Mean of 50 months | PCO2 61 to 44 | Dyspnea | ESS 16 to 6
|
|
| Masa et al. [43] | 22/Prospective | 41 | NIMV*** | 4 months to a year | PCO2 58 to 45 | Headaches
Dyspnea
Edema | Sleepiness
Morning drowsiness
|
|
| Pérez De Llano et al. [40] | 24/Prospective
| 44 | Bilevel PAP
titration
CPAP 10 | 24 hrs | PCO2 58 to 44 in Bi-level PAP
PCO2 60 to 42 in CPAP | | ESS |
|
| Priou et al. [44] | 130/Retro | 44 | Bilevel PAP
IPAP 14 to 28
EPAP 6 to 14 | 6 months | PCO2 56 to 45 | | ESS 10 to 4
AHI 87 to 13
|
|
| Murphy et al. [48] | 50/PR | 51 | Bilevel PAP 25/10
AVAPS:
volume = 657 mL
EPAP = 9 | 3 months | PCO2 51 to 47 in Bi-level PAP
PCO2 53 to 48 in AVAPS | | No between-group differences; intragroup comparisons not reported |
|
| Borel et al. [49] | 35/PR | 40 | Bilevel PAP
(versus counseling) | 1 month | PCO2 48 to 43
in Bi-level PAP | | REM 17 to 26%
AHI 40 to 6
In bi-level PAP |
|
