Clinical Study
Intravascular Talcosis due to Intravenous Drug Use Is an Underrecognized Cause of Pulmonary Hypertension
Table 1
Demographics for cases of talc granulomatosis.
| Case | Specimen | Sex | Age (years) | Admitted IVDU | Hep C | Tobacco smoking | Pulmonary symptoms/diagnoses |
| 1 | Autopsy | M | 37 | Yes | Negative | no | Dyspnea Pulmonary HTN | 2 | Autopsy | M | 40 | Yes | Positive | yes | | 3 | Autopsy | M | 62 | Yes, remote | Positive | no | | 4 | Autopsy | M | 55 | Yes, remote | Positive | yes | IPF Pulmonary HTN Recurrent pneumothoraces | 5 | Autopsy | F | 44 | Yes | Positive | yes | COPD | 6 | Transbronchial biopsy | M | 51 | Yes, remote | Positive | yes | Dyspnea Pulmonary HTN s/p R lung transplant for talc exposure* | 7 | Pneumonectomy due to trauma | M | 20 | NA | NA | NA | | 8 | Double lung transplant native lungs | M | 53 | No | Positive | yes | Dyspnea Mild pulmonary HTN | 9 | Wedge resection | M | 31 | No | NA | yes | Dyspnea Pleuritic chest pain Pulmonary HTN |
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*Initially diagnosed with talc pneumoconiosis. Abbreviations: HTN: hypertension, IPF: idiopathic pulmonary fibrosis, COPD: chronic obstructive pulmonary disease, s/p: status post, NA: not available.
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