Clinical Study
Do We Need Exercise Tests to Detect Gas Exchange Impairment in Fibrotic Idiopathic Interstitial Pneumonias?
Table 2
Cardiopulmonary exercise testing and walking test results.
| | All patients | IPF | f-NSIP | | n = 121 | n = 88 | n = 33 |
| | Workload, peak (Watts) | 81.4 24 | 82.5 23.7 | 78.3 25.9 | | Workload, peak (%) | 71.3 9.9 | 61.2 18.8 | 67.2 24.8 | | VO2, peak (mL/Kg/min) | 15.9 3.9 | 15.9 3.6 | 15.9 4.6 | | VO2, peak (%) | 66.5 15.7 | 66 15 | 67.8 17.7 | | % low VO2, peak (%) | 84 | 87 | 80 | | PaO2, peak (mmHg) | 57.9 13 | 56.6 12.9 | 61.6 12.6 | | ΔPaO2 (mmHg) | 18.9 8.3 | 19.4 8.5 | 17.6 7.8 | | P(A-a)O2, peak (mmHg) | 58.1 13 | 58.9 13.2 | 61.7 12.7 | | % with high P(A-a)O2, peak | 92.5 | 95 | 84 | | ΔP(A-a)O2/ΔVO2 (mmHg/L) | 34.2 16.9 | 34.4 17.1 | 33.6 16.7 | | % with high ΔP(A-a)O2/ΔVO2 | 83 | 82 | 84 | | VD/VT, peak | 0.43 0.09 | 0.44 0.09 | 0.39 0.08* | | Walk test, distance (m) | 388 102 | 393 98 | 375 114 | | Walt test, nadir SaO2 (%) | 86 5.7 | 85.6 6 | 88.3 4.6 | | Walk test, ΔSaO2 (%) | 9.2 4.7 | 9.7 5 | 7.9 3.7 | | % with ΔSaO2 ≥4% | 83 | 83 | 84 |
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*Significantly different from IPF group (P = 0.01).
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