Research Article
Successful Smoking Cessation in COPD: Association with Comorbidities and Mortality
Table 3
Underlining clinical characteristics that predict mortality of the COPD patients during the four-year followup.
| Variables | Patient N = 739 | Deceased % | Crude OR | 95% CI | P value | Adjusted OR | 95% CI | P value |
| Aging by one year | | | 1.05 | 1.02–1.09 | 0.002 | 1.07 | 1.03–1.11 | 0.001 | Gender | | | | | | | | | Male | 466 | 18.0 | 1.00 | | | 1.00 | | | Female | 259 | 11.6 | 0.60 | 0.38–0.93 | 0.022 | 0.81 | 0.48–1.435 | NS | Smoking cessation | | | | | | | | | Yes | 426 | 12.2 | 1.00 | | | 1.00 | | | No | 299 | 20.7 | 1.88 | 1.26–2.82 | 0.002 | 2.50 | 1.55–4.03 | <0.001 | Cardiovascular diseases | | | | | | | | | No | 514 | 13.0 | 1.00 | | | 1.00 | | | Yes | 211 | 22.3 | 1.91 | 1.26–2.89 | 0.002 | 1.52 | 0.94–2.46 | NS | Diabetes | | | | | | | | | No | 606 | 14.5 | 1.00 | | | 1.00 | | | Yes | 117 | 22.8 | 1.68 | 1.03–2.75 | 0.036 | 1.38 | 0.79–2.43 | NS | Alcohol abuse | | | | | | | | | No | 584 | 13.7 | 1.00 | | | 1.00 | | | Yes | 128 | 24.2 | 2.01 | 1.26–3.22 | 0.003 | 2.03 | 1.14–3.61 | 0.016 | Psychiatric condition | | | | | | | | | No | 544 | 14.9 | 1.00 | | | 1.00 | | | Yes | 175 | 17.1 | 1.18 | 0.75–1.87 | NS | 1.32 | 0.77–2.26 | NS | Cancer | | | | | | | | | No | 649 | 13.7 | 1.00 | | | 1.00 | | | Yes | 74 | 32.4 | 3.02 | 1.77–5.16 | <0.001 | 3.08 | 1.70–5.59 | <0.001 | FEV1 % of predicted | | | | | | | | | >80% | 87 | 5.7 | 1.00 | | | 1.00 | | | 80–65% | 191 | 9.9 | 1.81 | 0.65–5.02 | NS | 2.12 | 0.68–6.67 | NS | 65–40% | 306 | 16.5 | 3.24 | 1.25–8.40 | 0.015 | 3.76 | 1.27–11.15 | 0.017 | <40% | 136 | 28.7 | 6.59 | 2.48–17.51 | <0.001 | 8.77 | 2.88–26.68 | <0.001 |
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Response (dead = 1, alive = 0).
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