The Role of Cardiopulmonary Exercise Test in IPF Prognosis

Table 5

Relationships between the variables of both exercise tests and pulmonary function tests in the study population by Spearman’s rank correlation coefficient. 𝑃 value < 0.05 is considered significant.

	VE/VCO2 slope	VO2 peak/kg	Distance 6MWT	Desaturation 6MWT
FEV1%	𝑟=−0.26	𝑟=0.41	𝑟=0.4	𝑟=−0.47
	𝑃=0.2	𝑃=0.03	𝑃=0.05	𝑃=0.01
FVC%	𝑟=−0.38	𝑟=0.52	𝑟=0.48	𝑟=−0.5
	𝑃=0.06	𝑃=0.007	𝑃=0.01	𝑃=0.01
TLC%	𝑟=−0.36	𝑟=0.6	𝑟=0.61	𝑟=−0.47
	𝑃=0.08	𝑃=0.003	𝑃=0.002	𝑃=0.02
DLCO%	𝑟=−0.74	𝑟=0.64	𝑟=0.7	𝑟=−0.57
	𝑃<0.001	𝑃=0.001	𝑃<0.0001	𝑃=0.004

Minute ventilation (VE), carbon dioxide output (VCO₂), peak oxygen consumption/kg (VO₂ peak/kg), (FEV₁) forced expiratory volume at one second, (FVC) forced vital capacity, (TLC) total lung capacity, and (DLCO) diffusing capacity for carbon monoxide.