Pulmonary Medicine / 2014 / Article / Tab 5 / Review Article
Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis Table 5 Timetable of infections following LTX.
1st month 2nd–6th month >6 months Nosocomial infections* Respiratory tract infections Surgical site infections Urinary tract infections Catheter infection, sepsis Reactivation of latent infections + opportunistic infections Community-acquired infections/pneumonia Related more to surgery and intensive care Related more to immunosuppression CF lung pathogens: Pseudomonas spp. Burkholderia cepacia complex B. gladioli ; NTM Other bacteria: S. aureus Enterobacteriaceae Enterococci Acinetobacter spp. Fungi: Candida spp. (Aspergillus spp.) Viruses: Herpes simplex virus Respiratory viruses Viruses: Cytomegalovirus Epstein-Barr virus Herpes simplex virus Varicella Zoster virus Opportunists: P. jirovecii Toxoplasmosis Aspergillus spp. Nocardia Listeria Mycobacteria (especially NTM) CF-lung pathogens: Pseudomonas spp. Burkholderia spp. Viruses: Epstein-Barr virus Respiratory viruses Respiratory bacteria: S. pneumonia H.influenzae C. pneumoniae M. pneumoniae and others CF lung pathogens: Pseudomonas spp. Burkholderia spp. Fungi: Aspergillus spp. C. difficile infection**Late-onset C. difficile infection
May occur also in later periods after LTX depending on prolonged or recurrent hospitalisation and the presence of medical devices.
**Highest incidence within the first 3 up to 12 months after LTX in association with broad antimicrobial therapy and intense immunosuppression.