Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?

<div>Comparison of (a) mRNA expression levels of NOX4 determined by qRT-PCR and (b) MDA concentrations (nmol/L) determined by spectrophotometry of lung tissue from rats exposed to normoxia (NX), chronic intermittent hypoxia (CIH2x2), or chronic sustained hypoxia (CH). 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in each group.</div>

Pulmonary Medicine

fig5

Figure 5

Figure 5: Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension? 

Figure 5 | Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension? 