Research Article

Pulmonary Arterial Hypertension Specific Therapy in Patients with Combined Post- and Precapillary Pulmonary Hypertension

Table 1

Descriptive statistics of patients enrolled in the study.

Variable Patients who tolerated PAHST Patients who did not tolerate PAHST
Number of patientsMeanSENumber of patientsMeanSE

Age2064.62.93667.44.61
CCI203.800.3664.00.37
PAPm2051.32.71648.83.45
PAWP2023.60.84627.02.80
TPG2027.72.53621.82.27
PVR196.50.7867.142.47
DPG208.31.6564.22.06
CO194.460.2163.680.25
Vascular compromise1971.21.20671.42.47

WHO-baseline202.700.2163.000.37
WHO-3 months182.330.23
WHO-6 months182.220.21
WHO-9 months162.060.21
6-MWD-baseline23276.038.506268.050.52
6-MWD-3 months17360.529.01
6-MWD-6 months17343.922.99
6-MWD-9 months15364.634.85
6-MWD (% pre)-baseline2356.46.83658.38.99
6-MWD (% pre)-3 months1772.63.82
6-MWD (% pre)-6 months1772.83.58
6-MWD (% pre)-9 months1574.14.26
Survival (in days)201350.8173.44

PAHST = Pulmonary Arterial Hypertension Specific Therapy, CCI = Charlson Comorbidities Index, PAPm = Mean Pulmonary Artery Pressure (mmHg), PAWP = Pulmonary Arterial Wedge Pressure (mmHg), CO = Cardiac Output (L/min), TPG = Transpulmonary Gradient (mmHg), DPG = Diastolic Pressure Gradient (mmHg), PVR = Pulmonary Venous Resistance (WU), WHO = World Health Organization functional class, 6-MWD = 6-minute walk distance (meters), and SE = standard error.