PPAR Research
Volume 2008 (2008), Article ID 316306, 11 pages
doi:10.1155/2008/316306
Research Article

Statins Activate Human PPARα Promoter and Increase PPARα mRNA Expression and Activation in HepG2 Cells

Makoto Seo,1 Ikuo Inoue,2 Masaaki Ikeda,3,4 Takanari Nakano,1 Seiichiro Takahashi,2 Shigehiro Katayama,2 and Tsugikazu Komoda1

1Department of Biochemistry, Faculty of Medicine, Saitama Medical University, Saitama 350-0495, Japan
2Department of Endocrinology and Diabetes, Faculty of Medicine, Saitama Medical University, Saitama 350-0495, Japan
3Department of Physiology, Faculty of Medicine, Saitama Medical University, Saitama 350-0495, Japan
4Molecular Clock Project, Research Center for Genomic Medicine, Saitama Medical University, Saitama 350-0495, Japan

Received 17 June 2008; Revised 17 September 2008; Accepted 2 October 2008

Academic Editor: Howard Glauert

Copyright © 2008 Makoto Seo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Makoto Seo, Ikuo Inoue, Masaaki Ikeda, et al., “Statins Activate Human PPARα Promoter and Increase PPARα mRNA Expression and Activation in HepG2 Cells,” PPAR Research, vol. 2008, Article ID 316306, 11 pages, 2008. doi:10.1155/2008/316306