The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects

<table>Platelets promote inflammation. CD40 expressing cells, such as endothelial
cells or fibroblasts, can be activated by platelet-derived CD40L. CD40 signaling upregulates bioactive
mediators in these cells; therefore, potentiating inflammation and increasing
the risk for CVD.</table>

PPAR Research

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Figure 1

Figure 1: The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects 