Review Article
Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition
Table 2
Summary of PPAR expression patterns.
| (a) Global expression pattern | Gene | Species | Expression localization | References |
| PPARα | Rodents | Cardiomyocytes | [6, 8] | Hepatocytes | Human | Heart | [6, 8] | Kidney | Large intestine | Leydig and seminiferous tubule cells | [12] | Liver | [6, 8] | Skeletal muscle | Uterus | [12] | Ovary (Theca and stroma cells) |
| PPARβ | Rodents | Ubiquitous | [6, 8] | Human | Ubiquitous | [6, 8] |
| PPARγ | Rodents | Brown and white adipose tissue | [6, 8] | Lymphoid organs | Retina | Skeletal muscle | Uterus | [12] | Granulosa cells, corpus luteum | Human | Colon | [6, 8] | Kidney | Liver | Skeltal muscle | Vascular endothelium | White adipose tissue | Sertoli cells | [12] | Uterus | Granulosa cells |
| (B) Placental expression pattern |
| PPARα, β, γ | Rodents | Term placenta | [4, 9] | Human | Villous trophoblastic cells and syncytiotrophoblasts | [4, 9, 10] | Amnion, chorion, and amnion derived-WISH cell line |
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