Review Article
CXCR4 in Cancer and Its Regulation by PPARγ
Table 2
Rosiglitazone
downregulation of CXCR4 on HT-29 cells and suppression by PPAR antagonists. HT-29 cells were treated with
the PPAR antagonists (I) GW9662 at 1 M or (II) T0070907 at 100 nM for 30 minutes before exposure to
rosiglitazone (10 nM). Cell-surface CXCR4 protein expression was measured after
48 hours. The data are mean values ± SE
. The table is taken from [101] with permission.
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Significant change due to
rosiglitazone, ***; **; n.s.: not significant. |