Review Article

The Role of PPAR 𝛾 Receptors and Leukotriene B 4 Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer

Figure 1

Immunocytochemistry of PPARγ receptor in normal human pancreas and in a PanIN lesion and a pancreatic cancer. The PPARγ receptor antibody shows a similar intensity of nuclear staining in normal ducts and in pancreatic cancer cells as well as cells in the PanIN lesion. In contrast, no staining is seen in normal islets, but nuclear staining is seen in islets from tissue adjacent to a cancer. These pictures are representative of eight samples of each tissue type. Staining was similar using antibodies from two different commercial sources.
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