PPAR<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi mathvariant="bold">α</mml:mi></mml:math> Ligands as Antitumorigenic and Antiangiogenic Agents : Figure 1

]>PPAR<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi mathvariant="bold">α</mml:mi></mml:math> Ligands as Antitumorigenic and Antiangiogenic Agents : Figure 1

Figure 1: Schematic representation of the antiangiogenic and antitumorigenic properties of PPARα. PPARα ligands reduce tumor growth by direct inhibition of tumor cell functions (black pathway). In addition, they prevent tumor-associated angiogenesis via direct (red pathway) as well as indirect (green pathway) inhibition of endothelial cell functions.