The Development of INT131 as a Selective PPAR Modulator: Approach to a Safer Insulin Sensitizer
Figure 5
PPARγ activation by
INT131 is cell-type-dependent. Cell-based reporter assays were performed
by transfecting three different cell types (HEK293, CV-1, CHO) with the same
reporter construct and stimulating with increasing concentrations of
rosiglitazone (black) or INT131 (red). Adapted from [17].
