Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk?

<table>Number of events with antidiabetic drugs. The figure shows the effect of antidiabetic drugs (rosiglitazone, metformin, and glyburide) on various cardiovascular adverse events; <svg height="13.95" id="M20" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.162498 13.95" width="58.162498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> for the comparison between metformin and glyburide treatment groups and the rosiglitazone group. The figure is developed from the data of adverse events shown in the Diabetes Outcome Progression Trial (ADOPT) trial    [<a href="/journals/ppar/2009/460764/#B7">7</a>].</table>

PPAR Research

fig2

Figure 2

Figure 2: Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk? 