Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease

Table 3

Estimate of PPARG haplotype frequencies in cases and controls.

C-681G	C-689T	Pro12Ala	C1431T	Controls	Cases	P
PRIME Men
1	1	1	1	0.72	0.72
2	1	1	1	0.11	0.11
2	2	2	2	0.08	0.09	.53
2	2	2	1	0.04	0.03
1	1	1	2	0.03	0.03
2	1	1	2	0.01	0.02
ADVANCE Men
1	1	1	1	0.74	0.73
2	1	1	1	0.11	0.10
2	2	2	2	0.09	0.08	.38
2	2	2	1	0.03	0.04
1	1	1	2	0.02	0.02
2	1	1	2	0.02	0.01
ADVANCE Women
1	1	1	1	0.71	0.72
2	1	1	1	0.13	0.13
2	2	2	2	0.08	0.08	.70
2	2	2	1	0.04	0.03
1	1	1	2	0.03	0.03
2	1	1	2	0.01	0.01

Only haplotypes with a frequency >1% are displayed. 1 and 2 represent the frequent and minor alleles, respectively. 𝑃 value is for the global effect (5 df).