MBX-102/JNJ39659100, a Novel Non-TZD Selective Partial PPAR- Agonist Lowers Triglyceride Independently of PPAR- Activation
Figure 5
Effect of
MBX-102 (100 mg/kg) and fenofibrate (450 mg/kg) on fasting plasma insulin (a), triglycerides (b), and liver weights (c) after 32 days of treatment of male ZF rats. Values are
plotted as mean SEM (: , : versus ZF vehicle,
: , : , MBX-102 versus fenofibrate, 1-way ANOVA, and
Newman-Keuls multiple comparison test).
