MBX-102/JNJ39659100, a Novel Non-TZD Selective Partial PPAR- Agonist Lowers Triglyceride Independently of PPAR- Activation
Figure 6
Gene expression levels of
PPAR- responsive genes in
livers derived from male ZF rats treated for 32 days with either MBX-102
(100 mg/kg) or fenofibrate (450 mg/kg). Expression levels of ACO (a), HADHB (b), and apoC-III (c) mRNA.
Values
represent mean SEM (NS: , : versus Vehicle-treated, 1-way ANOVA, and Newman-Keuls multiple comparison
test).
