Impact of the Pro12Ala Polymorphism of the PPAR-Gamma 2 Gene on Metabolic and Clinical Characteristics in the Palestinian Type 2 Diabetic Patients

Table 1

Anthropometrical and biochemical parameters of the study groups. Data are in means ± SD. BMI =Body mass index; SBP=systolic blood pressure; DBP=diastolic blood pressure; TC: total cholesterol; TG: Triglyceride; FPG: fasting plasma glucose; NS: not significant; D: Diet; I: insulin; IO: Insulin and oral hypoglycemic agent; O: oral hypoglycemic agent.

Parameters	Obese subjects	Nonobese subjects	𝑃
	𝑛=121	𝑛=81
Sex (M/F)	31/90	33/48
Age (years)	58.6+10.1	59.9+10.1	NS
Age at diagnosis	49.8+10.1	49.6+10.5	NS
BMI (kg/m^2)	35.4+4.9	25.8+2.5	<.001
SBP (mmHg)	126.1+18.8	130.1+19.0	NS
DBP (mmHg)	78.6+9.3	79.6+14.8	NS
FPG (mg/dL)	208.4+84.0	211.3+80.3	NS
TC (mg/dL)	201.5+52.6	189.6+44.3	NS
TG (mg/dL)	181.4+78.9	167.5+83.5	NS
HDL (mg/dL)	43.6+16.0	41.3+13.4	NS
LDL (mg/dL)	120.1+48.5	109.6+44.9	NS
Therapy(n) D/I/IO/O	4/22/16/79	2/22/5/52	NS