PPAR𝛾 Ligand as a Promising Candidate for Colorectal Cancer Chemoprevention: A Pilot Study

Table 2

Effect of PPAR𝛾 ligand for human ACF and adenoma.

			Pre-treatment	Post-treatment	P value
Number of ACF	Control		5.4±4.0	5.6±5.8	>.05
	Pioglitazone		5.8±1.1	3.3±2.3	.0226
Number of Crypts/ACF	Control		16.8±5.2	17.8±6.4	>.05
	Pioglitazone		14.3±5.9	13.6±6.7	>.05
Number of adenoma	Control		2.0±1.0	1.8±0.8	>.05
	Pioglitazone		2.2±1.5	2.3±2.1	>.05
Mean size of adenoma (mm)	Control		6.9±3.2	7.0±3.3	>.05
	Pioglitazone		5.7±2.8	5.8±2.8	>.05
Location of maximum adenoma	Control	Right side	8	8
		Left side	12	12
	Pioglitazone	Right side	4	4
		Left side	5	5

Data are expressed as mean±SD.