Developmental Effects of Perfluorononanoic Acid in the Mouse Are Dependent on Peroxisome Proliferator-Activated Receptor-Alpha
Figure 2
Effect of prenatal exposure to PFNA on the percent of eyes open on postnatal days 13–16 in wild-type (WT) and PPAR knockout (KO) mouse pups. Data represent litter means SEM of the percent of the litter with pups having both eyes fully open. A reduction in the percent of eyes open was found in the WT pups exposed to 2 mg/kg PFNA. Differences were found by ANOVA and Bonferroni’s test for multiple comparisons. Asterisks denote a significant difference (, , ). PND: postnatal day.
