Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo

Figure 1

Graphic depicting the generation of mice conditionally expressing hPPARδ and hPPARδΔAF2 transgenes. Mice harbouring transgenes, encoding the coding sequence of hPPARδ or hPPARδΔAF2 fused to the rat Cyp1a1 gene promoter and offering tight control of XRE enhancer driven transgene expression.