Review Article

Peroxisome Proliferator-Activated Receptor Gamma and Regulations by the Ubiquitin-Proteasome System in Pancreatic Cancer

Figure 4

The TGFβ pathway and regulations by ubiquitination and PPARγ. Its deregulation by Smad4 mutations may lead to PPARγ upregulation in pancreatic carcinomas. Several components of TGFβ pathway are targets of ubiquitination with degradative and nondegradative outcomes.
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