Fatty Acid Accumulation and Resulting PPAR𝜶 Activation in Fibroblasts due to Trifunctional Protein Deficiency

Figure 3

PPRE-binding activity. Assay methods were described in Section 2. Open bar, PPARα; gray bar, PPARβ; closed bar, PPARγ. P1–P6, individual patient’s fibroblast; C1–C3, individual control fibroblast; P, means ± SD in six patients’ fibroblasts; C, means ± SD in three control fibroblasts. *𝑃<0.05, versus controls.