PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways

Table 1

Principal properties of the PON enzymes.

Enzyme	Gene expression	Protein expression	Present in circulation	Lactonase activity	Hydrolysis of lipid peroxides	Esterase activity
PON1	Ubiquitous	Ubiquitous strong	HDL	Yes	Yes	Yes
PON2	Ubiquitous	Ubiquitous weak	No	Yes	Yes	No
PON3	Ubiquitous	Ubiquitous strong	HDL	Yes	Yes	No