PPARG Epigenetic Deregulation and Its Role in Colorectal Tumorigenesis

Table 1

Effects of PPARγ expression/activation in different human tumors.

Tumor type	Supposed function	References
Colon cancer	Associated with good patients’ prognosis	[105, 106]
Hepatic cancer	Protective effect against cancer	[59]
Renal cell carcinoma	Potential target of pharmacological therapy	[45]
Prostate cancer	Potential target of pharmacological therapy	[45]
Ovarian cancer	Protective effect against cancer	[46]
B cell lymphoma	Potential target of pharmacological therapy	[104]
Ependymoma	Not defined	[143]
Breast cancer	Protective effect against cancer	[47, 50, 51]
Neuroblastoma	Protective effect against cancer	[52]
Pancreatic Cancer	Associated with shorter overall survival	[77]
Thyroid carcinoma	Protective effect against cancer	[48]
Liposarcoma	Induction of tumor differentiation	[49]