PPARG Epigenetic Deregulation and Its Role in Colorectal Tumorigenesis

Table 2

Effects of TZD administration on human cell lines derived from different tumors.

Cell types	Observed effects	References
Colorectal cancer	Growth arrest, differentiation, apoptosis	[39, 57, 67, 68, 70]
Thyroid carcinoma	Growth arrest	[54]
Prostate cancer	Growth arrest	[55]
Ependymoma	Growth arrest	[39]
Lung carcinoma	Cell cycle arrest	[58, 62, 69, 76]
Breast cancer	Cell cycle arrest	[56, 66]
Hepatoma	Cell cycle arrest	[59, 63]
Neuroblastoma	Increased proliferation	[81]
Pancreatic carcinoma	Cell cycle arrest	[60, 61]