Review Article

Peroxisome Proliferator-Activated Receptor Genetic Polymorphisms and Nonalcoholic Fatty Liver Disease: Any Role in Disease Susceptibility?

Table 1

Characteristics of the studies on the association between the PPAR polymorphisms and nonalcoholic fatty liver disease.

First author, yearRef.PPAR variantPopulation ethnicity, countrySample size ( )Patients characteristicsLiver biopsy ( )Female sex, (%)Conclusions

Chen, 2008[24]Val227AlaChina Unspecified NAFLD = not specified40 (51)Association with NAFLD
Dongiovanni, 2010[25]Leu162ValCaucasian, Italy Histological NAFLD 41 (20)No association with NAFLD

Ref: reference number; : number; NAFLD: nonalcoholic fatty liver disease.