Effects and Potential Mechanisms of Pioglitazone on Lipid Metabolism in Obese Diabetic KKAy Mice
Figure 4
Expression of adipocyte-specific genes in the liver and WAT of vehicle- and pioglitazone-treated KKAy mice. Gene expression in liver (a) and WAT (b), which was examined by using the real-time PCR. Results were expressed as fold change, after correction for β-actin levels, relative to the control mice. Nor, C57BL/6J mice; Con, vehicle-treated KKAy mice; Piog, pioglitazone-treated KKAy mice. Data are presented as mean ± S.E.M. (–8 per group). *, ** versus Con. PPARγ, peroxisome proliferator activated receptor gamma; FABP4/ap2, adipocyte fatty acid binding protein 4; LPL, lipoprotein lipase; FAT/CD36, fatty acid translocase/CD36 antigen; FSP27, fat specific protein 27; AdipoQ, adiponectin.
