PPAR-γ Regulates Trophoblast Differentiation in the BeWo Cell Model

Figure 1

PPAR-γ expression correlates inversely with its activity. (a) PPAR-γ mRNA expression levels overtime in response to rosiglitazone, T0070907, their combination, and forskolin treatment. (b) Cellular PPAR-γ protein expression at 48 hours of treatment (representative blot in the bottom panel). All treatments are compared to their respective vehicle controls (set as 1, red dashed line). Values are represented as mean ± SEM; ^#𝑃<0.05 versus vehicle control; *𝑃<0.05; **𝑃<0.005; ***𝑃<0.001 (𝑛=4). Ro/rosi, rosiglitazone; T/T007, T0070907; For, forskolin.

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