The Pro12Ala Polymorphism of PPAR-γ Gene Is Associated with Sepsis Disease Severity and Outcome in Chinese Han Population

Table 2

Distributions of genotypes and allele frequencies in controls and patients with sepsis.

Genotype	All sepsis cases,; 𝑛 (%)	Controls,; 𝑛 (%)	𝑃 value	𝑃 value*	OR (95% CI)
Total	308	345	0.622	0.629	1.160 (0.642–2.098)
Pro12Pro	287 (93.18)	318 (92.17)
Pro12Ala	21 (6.82)	27 (7.83)
Ala12Ala	0 (0)	0 (0)
Allele
Pro	595 (96.59)	663 (96.09)	0.629	0.629	1.154 (0.645–2.063)
Ala	21 (3.41)	27 (3.91)

OR: odds ratio; 95% CI: 95% confidence interval. ∗False discovery rate adjusted  𝑃 value for multiple hypothesis testing using the Benjamini-Hochberg method.