PGC1α −1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals

Figure 3

Anthropometric measures in individuals with alternate −1 nucleosome positioning within the PGC1 promoter. Individuals were divided into upstream (UP, black) and downstream (DN, white) groups and (a) body weight, body mass index (BMI), and percent body fat and lean mass, (b) systolic (SBP) and diastolic blood pressure (DBP), (c) total, high density lipoprotein (HDL), and low density lipoprotein (LDL) cholesterol, and (d) plasma triglycerides, free fatty acids (FFA), glucose, and insulin were analyzed by Student’s -test and are shown as . ∗ indicates significance difference between groups with .

(a) Body weight and composition

(b) Blood pressure

(c) Cholesterol

(d) Triglycerides, free fatty acid, and insulin sensitivity