Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism

Figure 5

Crystal structure of a representative cercosporamide PPARγ partial agonist. (a) Poseview map of Compound 23. (b) Crystal structure of Compound 23 bound to the PPARγ ligand binding domain. PDB: 3LMP [55]. The branches of the ligand binding pocket have been labelled with Roman numerals.

(a)

(b)