15-Deoxy-Δ^12,14-Prostaglandin J₂ Inhibits Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury via Redox Pathway

Figure 5

The effect of 15d-PGJ₂ on F-actin remodeling in BMSCs. ((a) and (b)) BMSCs were incubated with FITC-conjugated phalloidin to identify F-actin (green) in the absence (a) or presence (b) of 15d-PGJ₂ (5 μM). Focal adhesion-like structures were shown as arrows in (a). ((c) and (d)) High content analysis was used to determine the number of fibers (c) and fiber alignment (d) in BMSCs after 15d-PGJ₂ treatment at the indicated time points. , compared with control (). Scale bars, 50 μm.

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