Research Article

Pioglitazone Protected against Cardiac Hypertrophy via Inhibiting AKT/GSK3β and MAPK Signaling Pathways

Figure 4

PIO alleviated hypertrophy of cardiac myocytes in vitro. (a) The effects of PIO on viability of neonatal rat ventricular cardiomyocytes were determined by CCK-8 in 5 independent experiments. (b) The levels of ANP of cardiomyocytes in indicated groups (). (c) The immunofluorescence of cardiomyocytes and the sectional areas of myocytes (). .
(a)
(b)
(c)