Differential Roles of Peroxisome Proliferator-Activated Receptor-α and Receptor-γ on Renal Crystal Formation in Hyperoxaluric Rodents

Figure 6

Evaluation for apoptotic cells in model rat kidneys. (a) Representative micrographs of TUNEL-stained renal sections obtained on day 14. Magnification: 400x. Scale bar = 50 μm. (b) The average number of TUNEL-positive cells per high power field (400x; fields per group). Data are presented as mean ± SE. among EG + α, EG + γ, and EG + αγ groups; compared to the control group; compared to the EG group. (c) Western blotting of rat kidneys for caspase-9 and caspase-3 protein levels. The molecular mass of procaspase-9, cleaved caspase-9, and caspase-3 was confirmed by bands at 51, 37, and 35 kDa, respectively.

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