PPARG: A Promising Therapeutic Target in Breast Cancer and Regulation by Natural Drugs

Figure 1

Pan-cancer and ER+/− BC analysis of PPARG expression. (a and b) PPARG expression in tumor and normal tissues in TCGA and TCGA + GTEx pancarcinoma data, the result shows that PPARG is downregulated in BC. (c and d) PPARG expression in ER+ BC and normal tissues in TCGA and TCGA + GTEx data, compared with normal tissues, PPARG is downregulated in ER+ BC. (e and f) PPARG expression in ER− BC and normal tissues in TCGA and TCGA + GTEx data, compared with normal tissues, PPARG is downregulated in ER− BC. (g) PPARG expression in BC and normal tissues in GEPIA data, the expression of PPARG is lower in BC than in normal tissue. (h) Differential expression of PPARG in ER+ and ER− BCs, the expression of PPARG is higher in ER+ BC than in ER− BC. *, **, and ***.

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