Morphological Analysis of CDC2 and Glycogen Synthase Kinase 3β Phosphorylation as Markers of G2 → M Transition in Glioma

Table 1

Immunohistochemical labeling profiles in glioma. Immunohistochemical labeling for pThr161CDC2, pTyr15CDC2, pSer9GSK3𝛽 and EGFR are represented in each glioma cohort. Numbers represent total number of patients with high (H), intermediate (I), or low (L) labeling indexes.

	Mean age	n	pThr161CDC2			pTyr15CDC2			pSer9GSK3𝛽			EGFR
			H	L	I	H	L	I	H	L	I	H	L	I
Glioblastoma, WHO IV	53.6	45	31	4	10	26	7	12	20	14	11	5	11	29
Anaplastic Oligodenroglioma, WHO III	46	17	8	3	6	4	3	8	10	2	5	0	1	16
Oligodendroglioma, WHO II	38.5	20	2	3	15	2	1	17	7	6	7	0	2	19
Ependymoma, WHO II (Pediatric)	6.2	9	2	1	6	0	2	6	1	2	6	0	0	9
Ependymoma, WHO II (Adult)	37.8	11	0	0	11	0	1	10	1	3	7	0	0	11