Research Article
Association between AgNORs and Immunohistochemical Expression of ER, PR, HER2/neu, and p53 in Breast Carcinoma
Table 1
Association between mean AgNOR counts and different variables.
| Variables | AgNORs count | Mean of AgNORs | value | | | ≤2 dots/cell | >2 dots/cell |
| Age | ≤40 | 15 | 36 | 2.49 | 0.73 | >40 | 23 | 63 | 2.67 |
| ER | +ve | 26 | 47 | 2.45 | 0.05 | −ve | 12 | 52 | 2.71 |
| PR | +ve | 22 | 32 | 2.36 | 0.010 | −ve | 16 | 67 | 2.71 |
| HER2 | +ve | 8 | 27 | 2.58 | 0.997 | −ve | 30 | 72 | 2.57 |
| P53 | +ve | 14 | 52 | 2.81 | 0.001 | −ve | 24 | 47 | 2.36 |
| Histological type | IDC | 32 | 92 | 2.60 | 0.351 | NIDC | 6 | 7 | 2.38 |
| Tumor size | <2 cm | 1 | 6 | 2.80 | 0.747 | 2–5 cm | 20 | 54 | 2.50 | >5 cm | 6 | 19 | 2.66 |
| Tumor grade | Grade I | 7 | 15 | 2.40 | 0.022 | Grade II | 16 | 32 | 2.37 | Grade III | 0 | 17 | 3.41 |
| Lymph node status | −ve LN | 4 | 16 | 2.44 | 0.681 | +ve LN | 18 | 43 | 2.52 |
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