Clinical Study
Human Papillomavirus Types 52 and 58 Are Prevalent in Uterine Cervical Squamous Lesions from Japanese Women
| | No. of cases | HPV type | | Multiplex PCR | Positive for HPV | 6 | 11 | 16 | 18 | 30 | 31 | 33 | 35 | 39 | 45 | 51 | 52 | 56 | 58 | 59 | 66 |
| NILM* | 2068 | 194 | 11 (5) | 3 (1) | 30 (12) | 21 (7) | 5 (2) | 11 (3) | 8 (4) | 3 | 20 (7) | 1 | 15 (8) | 46 (19) | 18 (3) | 33 (13) | 4 (1) | 15 (5) | ASC-US | 169 | 77 | 4 (1) | — | 5 (1) | 4 (1) | 1 | 4 (2) | 5 (2) | 6 (1) | 5 (1) | 1 | 10 (1) | 21 (2) | — | 17 (7) | — | 5 (1) | ASC-H | 25 | 17 | — | — | 5 (2) | — | — | 3 | 2 (2) | 1 | 2 (2) | — | 1 (1) | 4 (2) | — | 3 (1) | 2 (1) | — | LSIL | 447 | 291 | 19 (12) | — | 51 (28) | 20 (13) | 3 (1) | 20 (13) | 12 (6) | 7 (5) | 27 (15) | 7 (4) | 31 (15) | 74 (38) | 45 (14) | 64 (35) | 11 (8) | 31 (17) | HSIL | 449 | 374 | 5 (5) | 1 (1) | 126 (59) | 22 (12) | 5 (4) | 38 (18) | 18 (10) | 6 (3) | 24 (14) | 5 (5) | 34 (20) | 110 (53) | 16 (8) | 96 (47) | 5 (4) | 19 (15) | SCC | 105 | 82 | 2 (2) | — | 44 (14) | 6 (3) | 1 (1) | 7 (3) | 7 (4) | 1 | 1 | — | 5 (5) | 21 (11) | 1 (1) | 13 (7) | — | 3 (1) |
| Total | 3263 | 1035 | 41 (25) | 4 (2) | 261 (116) | 73 (36) | 15 (8) | 83 (39) | 52 (28) | 24 (9) | 79 (39) | 14 (9) | 96 (50) | 276 (125) | 80 (26) | 226 (110) | 22 (14) | 73 (39) |
|
|
Number in the parenthesis: number of cases with multiple HPV infections. Patients who were randomly selected from 9760 NILM patients.
|