Review Article
Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis
Table 3
Frequency of high-risk HPV and p53 codon 72 polymorphism in exfoliated cervical cell samples.
| Lesions | Number with high-risk HPV | Aminoacid at p53 codon 72 | Arg | Arg/Pro | Pro |
| Normal () | 10 (18.5%)a | 24 (44.4%) | 23 (42.6%) | 7 (13.0%) | LSIL () | 28 (27.5%)b | 38 (37.3%) | 40 (39.2%) | 24 (23.5%) | HSIL () | 31 (73.8%)a, b | 18 (42.9%) | 16 (38.1%) | 8 (19.0%) |
|
|
a, OR = 12.4 ββversus normal. b, OR = 7.4 ββversus LSIL.
|