Review Article

Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis

Table 9

HPV status and frequency of Fas promoter -670 polymorphism in exfoliated cervical cell samples.

Study group š‘› Genotype at Fas promoter -670OR95% CI š‘ƒ f
AAGA + GG

High-risk HPVāˆ’
ā€ƒNormal5315 (28.3%)38 (71.7%)1
ā€ƒLSIL12136 (29.8%)85 (70.2%)0.930.44ā€“1.95.847
ā€ƒHSIL91 (11.1%)8 (88.9%)3.160.40ā€“25.04.276

High-risk HPV+
ā€ƒNormal104 (40.0%)6 (60.0%)1
ā€ƒLSIL4615 (32.6%)31 (67.4%)1.380.34ā€“5.66.655
ā€ƒHSIL404 (10.0%)36 (90.0%)6.001.32ā€“27.37.021

OR: odds ratio.
CI: confidence interval.