Review Article

Recognition of Dual or Multiple Pathology in Skin Biopsies from Patients with HIV/AIDS

Figure 7

(a) AIDS-associated Kaposi sarcoma with concomitant cutaneous cryptococcosis. Cryptococcus neoformans yeasts (including capsule deficient forms) are present amid the background spindle cell proliferation (b), with the mucicarmine preparation (c) highlighting the mucoid capsule around individual yeasts; narrow-based budding is present (inset). The KS lesional cells demonstrate immunoreactivity for both CD31 (d) and human herpes virus type 8 (HHV-8) (e).
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(a)
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(b)
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(c)
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(d)
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(e)