Research Article
Rosiglitazone-Mediated Effects on Skeletal Muscle Gene Expression Correlate with Improvements in Insulin Sensitivity in Individuals with HIV-Insulin Resistance
Table 2
Gene expression in muscle tissue of insulin-resistant HIV infected subjects before and after treatment with rosiglitazone.
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All gene expression data before and after treatment with rosiglitazone (8 mg/d for 12 weeks) are expressed as means ± SEM and normalized to the expression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). LPL: lipoprotein lipase; CPT-1: carnitine palmitoyl transferase-1; PPARγ: peroxisome proliferator-activated receptor γ; ACPR30: Adiponectin; SCD: steroyl CoA-desaturase; and PPARα: peroxisome proliferator-activated receptor α. Statistical significance was determined with a paired -test (SPSS). |