Research Article
Basal-Like Phenotype in a Breast Carcinoma Case Series from Sudan: Prevalence and Clinical/Pathological Correlations
Table 3
Basal cytokeratins status according to tumor grade, tumor size (), ER, PgR, combined ER/PgR, Her-2/neu, and histology.
| | CK5/6+ and/or CK17+, Number (%) | | Positive | Negative | χ 2 |
| | Grade | | | | | g2 | 9 (20) | 26 (39) | 4.72 () | | g3 | 37 (80) | 41 (61) | | Tumor size () | | | | | 1 | 4 (9) | 6 (9) | 0.67 () | | 2 | 21 (45.5) | 25 (37) | | 3 | 7 (15) | 13 (19.5) | | 4 | 5 (11) | 7 (10.5) | | NA¶ | 9 (19.5) | 16 (24) | | ER | | | | | ER+ | 21 (46) | 50 (75) | 9.8 () | | ER− | 25 (54) | 17 (25) | | PgR | | | | | PgR+ | 23 (50) | 51 (76) | 8.2 () | | PgR− | 23 (50) | 16 (24) | | Combined ER/PgR | | | | | ER+ and/or PgR+ | 25 (54) | 58 (87) | 14.5 () | | ER−/PgR− | 21 (46) | 9 (13) | | Her-2/neu | | | | | Her-2/neu+ | 10 (22) | 14 (21) | 0.012 () | | Her-2/neu− | 36 (78) | 53 (79) | | Histology | | | | | IDC* | 45 (98) | 56 (84%) | 6.3 () | | ILC° | — | 5 (7%) | | Mucinous | 1 (2) | 4 (6%) | | Medullary | — | 1 (1.5%) | | Paget’s disease | — | 1 (1.5%) |
|
|
¶NA: not available tumor size data in 25 cases, *IDC: infiltrating ductal carcinoma, °ILC: infiltrating lobular carcinoma.
|
