Blood-Brain Barrier Integrity and Breast Cancer Metastasis to the Brain

Table 1

ECM molecules	Candidate or demonstrated receptors	Collagen	Integrins (a1fl1, a2fl1, a3/.3), CD44, syndecan, proteoglycans
Laminins	Integrins (a13, a2fl, a3f3, a6fl, and a7j3; avjIs, a6fl4), dystroglycan, lactose-binding lectins, proteoglycans	Thrombospondins	Integrins avfls, avj3x, axfij, CD36, syndecan, proteoglycans, sulfatides
		Tenascin	Fl 1, integrins (axflj) syndecan, cytotactin binding proteoglycans
Fibronectin	Integrins (av/33, avf36, asfli, a5fl), CD44, syndecan, proteoglycans	Proteoglycans	Hyaluronan, integrins