The Prognostic Value of Lymph Node Cross-Sectional Cancer Area in Node-Positive Breast Cancer: A Comparison with N Stage and Lymph Node Ratio

Table 3

Multivariate analysis of the prognostic factors by Cox’s regression model in node-positive patients (𝑛=107).

Variable	Hazard Ratio	95% CI	𝑃-value
Age (continuous)	0.99	0.97–1.03	0.887
T1 versus (T2 + T3 + T4)	0.88	0.33–2.34	0.791
Tumor size (continuous)	1.12	0.99–1.26	0.071
Histologicgrade(G1+G2versusG3)	3.52	1.66–7.48	0.001
ERexpression(yesversusno)	0.39	0.19–0.81	0.012
ECE (yes versus no)	0.73	0.26–2.07	0.550
metLN (continuous)	0.93	0.01–1.018	0.052
LNR(continuous)	25.02	5.37–116.59	0.001
LN cancer area (continuous)	2.24	0.45–11.09	0.323