Endoscopic-Ultrasound-Guided Fine-Needle Aspiration and the Role of the Cytopathologist in Solid Pancreatic Lesion Diagnosis
Figure 11
Pancreatic neuroendocrine tumor: (a) normal pancreatic acini, Diff-Quik stain at 400x; (b) cohesive 3-dimensional cluster in Diff-Quik stain at 200x; (c) discohesive cells with salt and pepper chromatin and rare pinpoint nucleolus in cell block H&E at 400x; Immunohistochemical profile of the tumor: (d) cytokeratin AE1/AE3 highlights residual ductal epithelium but not the tumor, at 100x; (e) synaptophysin, strong and diffuse positivity, at 400x; (f) positive cytokeratin Cam 5.2 at 200x; (g) positive chromogranin at 400x.
