New Evidence-Based Treatment Approach in Behçet's Disease

Table 2

Summary of evidence-based algorithmic treatment for mucocutaneous Behçet’s disease.

1st line	*Topical: Antimicrobial agents, Sucralfate, Corticosteroids, Pimecrolimus
	Systemic: Colchicine, Colchicine + Benzathine penicillin
2nd line	*Topical: Anti-inflammatory agents, Amlexanox
	Systemic: Corticosteroids, Dapsone, Azathioprine, Thalidomide
3rd line	*Topical: Anaesthetics, Silver nitrate
	Systemic: Zinc sulfate, Rebamipide, Pentoxifylline, Methotrexate, Cyclosporine-A, IFN-α, Anti-TNF-α

*Since the effectiveness of topical treatment is generally limited to the application area, it should almost always be associated with systemic therapy.